U.S. Route 395 Business may refer to:
- U.S. Route 395 Business (Carson City, Nevada), running through downtown Carson City, Nevada
- U.S. Route 395 Business (Reno, Nevada), running through Reno, Nevada
- U.S. Route 395 Business (Ridgecrest, California), running through Ridgecrest, California
This disambiguation page lists articles about roads and streets with the same name.
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