Route information | ||||
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Maintained by VDOT | ||||
Length | 69.23 mi[1] (111.41 km) | |||
Existed | ca. 1950–present | |||
Tourist routes | Virginia Byway | |||
Major junctions | ||||
South end | US 421 / SR 34 in Bristol | |||
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North end | US 421 near St. Charles | |||
Location | ||||
Country | United States | |||
State | Virginia | |||
Counties | City of Bristol, Washington, Scott, Lee | |||
Highway system | ||||
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U.S. Route 421 (US 421) is a part of the U.S. Highway System that runs from Fort Fisher, North Carolina to Michigan City, Indiana. In Virginia, the U.S. Highway runs 69.23 miles (111.41 km) from the Tennessee state line between the twin cities of Bristol, Tennessee and Bristol, Virginia north and west to the Kentucky state line near St. Charles. Between its endpoints, US 421 has lengthy concurrencies with US 23 and US 58 during its course through Bristol, Weber City, Gate City, Duffield, and Pennington Gap in Southwest Virginia.