This article is about the section of U.S. Route 45 in Kentucky. For the entire route, see
U.S. Route 45.
U.S. Highway in Kentucky
U.S. Route 45 (US 45) enters Kentucky at Fulton in Fulton County and travels northeast through Hickman County, Graves County, and McCracken County. After passing through Mayfield in Graves County it heads directly north into Paducah as a four-lane highway. In Paducah, US 45 serves as a major artery, intersecting with Interstate 24 at Exit 7, and intersecting US 60 and 62. U.S. 45 leaves Kentucky from Paducah's northern border across the two-lane, metal-grate Brookport Bridge to Brookport, Illinois across the Ohio River.