U.S. Route 65 in Missouri

U.S. Route 65
US 65 highlighted in red
Route information
Maintained by MoDOT
Length	313.114 mi[1] (503.908 km)
Major junctions
South end	US 65 at the Arkansas state line
Major intersections	US 160 north of Branson US 60 in Springfield I-44 in Springfield US 54 in Preston US 50 in Sedalia I-70 south of Marshall US 24 in Carrollton US 36 / Route 110 (CKC) in Chillicothe US 136 in Princeton
North end	US 65 at the Iowa state line
Location
Country	United States
State	Missouri
Counties	Taney, Christian, Greene, Dallas, Hickory, Benton, Pettis, Saline, Lafayette, Carroll, Livingston, Grundy, Mercer
Highway system
United States Numbered Highway System List Special Divided Missouri State Highway System Interstate US State Supplemental
← Route 64 → US 66

U.S. Route 65 (US 65) is a north–south U.S. highway that runs from Clayton, Louisiana to Albert Lea, Minnesota. In Missouri, the highway enters the state from Arkansas, just south of Branson. The highway exits the state into Iowa near South Lineville.