U.S. Route 80 (US 80) is a 296-mile-long (476 km) U.S. Highway in the U.S. state of Georgia. It travels west-to-east from the Alabama state line in Columbus across the central portion of the state through cities such as Macon, Dublin, Statesboro, and Savannah to connect to its eastern terminus at an intersection with Tybrisa Street and Inlet Avenue in Tybee Island, near the Atlantic Ocean. Here, the roadway continues as Butler Avenue. US-80 is the main east-west non-Interstate route through Georgia.
In Georgia, all U.S. Highways have at least one state highway that travel concurrently along its route. The main ones that US 80 use are SR 540 from the Alabama state line to Geneva and in the eastern part of the Macon metropolitan area; SR 22 from the Alabama state line to Macon; SR 19 from Macon to a point southeast of Montrose; and SR 26 from that point to Tybee Island. From Macon to its Savannah, US 80 roughly parallels I-16, taking a more circuitous route to pass through the center several small towns that I-16 bypasses.