UGT2B4

UGT2B4
Identifiers
Aliases	UGT2B4, HLUG25, UDPGT2B4, UDPGTH1, UDPGTh-1, UGT2B11, UDP glucuronosyltransferase family 2 member B4
External IDs	OMIM: 600067; MGI: 1919023; HomoloGene: 130717; GeneCards: UGT2B4; OMA:UGT2B4 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	69,526,014 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	87,074,389 bp
RNA expression pattern
	Top expressed in
	liver; ; right lobe of liver; ; gonad; ; testicle; ; left ventricle; ; right auricle; ; right ventricle; ; myocardium; ; islet of Langerhans; ; myocardium of left ventricle;
	Top expressed in
	left lobe of liver; ; embryo; ; lumbar subsegment of spinal cord; ; right ventricle; ; tibiofemoral joint; ; sexually immature organism; ; medial head of gastrocnemius muscle; ; lumbar spinal ganglion; ; stria vascularis; ; carotid body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; glucuronosyltransferase activity; retinoic acid binding; hexosyltransferase activity; UDP-glycosyltransferase activity;
Cellular component	integral component of membrane; organelle membrane; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; membrane;
Biological process	cellular glucuronidation; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	7363
	71773
	ENSG00000156096
	ENSMUSG00000035836
	P06133
	Q8R084
	NM_001297615; NM_001297616; NM_021139
	NM_152811
	NP_001284544; NP_001284545; NP_066962
	NP_690024
	Wikidata
View/Edit Human	View/Edit Mouse

UDP glucuronosyltransferase 2 family, polypeptide B4, also known as UGT2B4, is an enzyme that in humans is encoded by the UGT2B4 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156096 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035836 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4".
^ Jackson MR, McCarthy LR, Harding D, Wilson S, Coughtrie MW, Burchell B (March 1987). "Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA". Biochem. J. 242 (2): 581–8. doi:10.1042/bj2420581. PMC 1147744. PMID 3109396.
^ Monaghan G, Clarke DJ, Povey S, See CG, Boxer M, Burchell B (September 1994). "Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13". Genomics. 23 (2): 496–9. doi:10.1006/geno.1994.1531. PMID 7835904.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156096 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035836 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4".

[pmid3109396-6] Jackson MR, McCarthy LR, Harding D, Wilson S, Coughtrie MW, Burchell B (March 1987). "Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA". Biochem. J. 242 (2): 581–8. doi:10.1042/bj2420581. PMC 1147744. PMID 3109396.

[pmid7835904-7] Monaghan G, Clarke DJ, Povey S, See CG, Boxer M, Burchell B (September 1994). "Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13". Genomics. 23 (2): 496–9. doi:10.1006/geno.1994.1531. PMID 7835904.

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