USS Bristol has been the name of two ships of the United States Navy, named in honor of Rear Admiral Mark Lambert Bristol.
- USS Bristol (DD-453), a Gleaves-class destroyer commissioned in 1941 and sunk off Algeria in 1943
- USS Bristol (DD-857), an Allen M. Sumner-class destroyer commissioned in 1945 and served until late 1969 after which it was then transferred to Taiwan
USS Bristol may also refer to: