USS Defiance

USS Defiance may refer to the following ships of the United States Navy:

• USS Defiance (ID-3327), a cargo vessel in service from 1918–1919
• USS Defiance (AMc-73), a coastal minesweeper that served during World War II
• USS Defiance (PG-95), a patrol gunboat that served from 1969 until 1973 when it was transferred to Turkey