Upu is a historical region surrounding Damascus.
Upu or UPU may also refer to:
- Upu, a village in Motusa, Fiji
- Melisa Upu (born 1974), New Zealand softball player
- Unpentunium, a hypothetical chemical element
- Universal Postal Union, a specialized agency of the United Nations
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This disambiguation page lists articles associated with the title Upu.
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