Vel blood group

Small integral membrane protein 1 (Vel blood group antigen)
Identifiers
SymbolSMIM1
HGNC44204
OMIM615242
RefSeq388588
UniProtB2RUZ4
Other data
LocusChr. 1 p36.32
Search for
StructuresSwiss-model
DomainsInterPro

The Vel blood group is a human blood group that has been implicated in hemolytic transfusion reactions.[1] The blood group consists of a single antigen, the high-frequency Vel antigen, which is expressed on the surface of red blood cells. Individuals are typed as Vel-positive or Vel-negative depending on the presence of this antigen. The expression of the antigen in Vel-positive individuals is highly variable and can range from strong to weak. Individuals with the rare Vel-negative blood type develop anti-Vel antibodies when exposed to Vel-positive blood, which can cause transfusion reactions on subsequent exposures.[2]

  1. ^ Cite error: The named reference Harmening2012 was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference OMIM was invoked but never defined (see the help page).