Vildagliptin/metformin

Vildagliptin/metformin
Combination of
VildagliptinDipeptidyl peptidase-4 inhibitor
MetforminBiguanide antihyperglycemic agent
Clinical data
Trade namesEucreas, Galvumet, Zomarist, others
AHFS/Drugs.comUK Drug Information
Routes of
administration		By mouth
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)[1][2]
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
KEGG

Vildagliptin/metformin, sold under the brand name Eucreas among others, is a fixed-dose combination anti-diabetic medication for the treatment of type 2 diabetes.[3] It was approved for use in the European Union in November 2007,[4] and the approval was updated in 2008.[5][6][7] It combines 50 mg vildagliptin with either 500, 850, or 1000 mg metformin.[8]

The most common side effects include nausea (feeling sick), vomiting, diarrhea, abdominal (tummy) pain and loss of appetite.[4][6][7]

  1. ^ "Eucreas 50 mg/850 mg film-coated tablets - Summary of Product Characteristics (SmPC)". (emc). 10 May 2018. Retrieved 8 June 2020.
  2. ^ "Eucreas 50 mg/1000 mg film-coated tablets - Summary of Product Characteristics (SmPC)". (emc). Retrieved 8 June 2020.
  3. ^ Halimi S, Schweizer A, Minic B, Foley J, Dejager S (2008). "Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet". Vascular Health and Risk Management. 4 (3): 481–92. doi:10.2147/vhrm.s2503. PMC 2515409. PMID 18827867.
  4. ^ a b "Eucreas EPAR". European Medicines Agency (EMA). Retrieved 8 June 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  5. ^ "EU approves Novartis's Eucreas diabetes drug". Reuters. 25 February 2008.
  6. ^ a b "Icandra EPAR". European Medicines Agency (EMA). Retrieved 8 June 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  7. ^ a b "Zomarist EPAR". European Medicines Agency (EMA). Retrieved 8 June 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  8. ^ "Galvumet".