Virus inactivation

Viral inactivation is to stop the viruses in a given sample from contaminating the desired product either by removing viruses completely or rendering them non-infectious. These techniques are used widely in the food and blood plasma[1] industries, as those products can be harmed by the presence of viral particles. Some of the more common viruses removed by these methods are the HIV-1 and HIV-2 viruses; hepatitis A, B, and C; and parvoviruses.[2] These methods have been adapted to remove prions, which are not related to viruses, from blood products.[3]

  1. ^ Shander A, Lobel GP, Javidroozi M (June 2016). "Transfusion practices and infectious risks". Expert Review of Hematology. 9 (6): 597–605. doi:10.1586/17474086.2016.1164593. PMID 26959944. S2CID 36732554.
  2. ^ Di Minno G, Perno CF, Tiede A, Navarro D, Canaro M, Güertler L, Ironside JW (January 2016). "Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders". Blood Reviews. 30 (1): 35–48. doi:10.1016/j.blre.2015.07.004. PMC 7115716. PMID 26381318.
  3. ^ Turner ML (2018). "Safety of blood, blood derivatives, and plasma-derived products". Human Prion Diseases. Handbook of Clinical Neurology. Vol. 153. pp. 463–472. doi:10.1016/B978-0-444-63945-5.00026-X. ISBN 978-0-444-63945-5. PMID 29887153.