WHO-CHOICE (CHOosing Interventions that are Cost-Effective) is an initiative started by the World Health Organization in 1998 to help countries choose their healthcare priorities.[1][2][3] It is an example of priority-setting in global health. It was one of the earliest projects to perform sectoral cost-effectiveness analyses (i.e., cost-effectiveness analyses that compare a wide range of types of spending within a sector and prioritize holistically) on a global scale.[4][5][6] Findings from WHO-CHOICE have shaped the World Health Report of 2002,[7] been published in the British Medical Journal in 2012,[1] and been cited by charity evaluators and academics alongside DCP2 and the Copenhagen Consensus.[8][9][10]