WNT10A

WNT10A
Identifiers
Aliases	WNT10A, OODD, SSPS, STHAG4, Wnt family member 10A
External IDs	OMIM: 606268; MGI: 108071; HomoloGene: 22525; GeneCards: WNT10A; OMA:WNT10A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	218,899,581 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	74,843,338 bp
RNA expression pattern
	Top expressed in
	gonad; ; bone marrow cells; ; skin of abdomen; ; skin of leg; ; granulocyte; ; lymph node; ; pituitary gland; ; mucosa of transverse colon; ; olfactory zone of nasal mucosa; ; anterior pituitary;
	Top expressed in
	tooth; ; molar; ; prostatic epithelium; ; inner root sheath; ; gastrula; ; epithelium of male urethra; ; enamel knot; ; lip; ; urethral gland (male); ; corneal stroma;
	More reference expression data
	n/a
Gene ontology
Molecular function	frizzled binding; signaling receptor binding; receptor ligand activity;
Cellular component	extracellular region; extracellular space;
Biological process	skin development; odontogenesis; tongue development; hair follicle development; positive regulation of gene expression; regulation of odontogenesis of dentin-containing tooth; multicellular organism development; neural crest cell differentiation; neuron differentiation; epidermis morphogenesis; hair follicle morphogenesis; cell fate commitment; cellular response to transforming growth factor beta stimulus; sebaceous gland development; Wnt signaling pathway; regulation of signaling receptor activity; canonical Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	80326
	22409
	ENSG00000135925
	ENSMUSG00000026167
	Q9GZT5
	P70701
	NM_025216
	NM_009518
	NP_079492
	NP_033544
	Wikidata
View/Edit Human	View/Edit Mouse

Wnt-10a is a protein that in humans is encoded by the WNT10A gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135925 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026167 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: wingless-type MMTV integration site family".
^ Kirikoshi H, Sekihara H, Katoh M (May 2001). "WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells". Biochem. Biophys. Res. Commun. 283 (4): 798–805. doi:10.1006/bbrc.2001.4855. PMID 11350055.
^ Adaimy L, Chouery E, Megarbane H, Mroueh S, Delague V, Nicolas E, Belguith H, de Mazancourt P, Megarbane A (October 2007). "Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia". Am. J. Hum. Genet. 81 (4): 821–8. doi:10.1086/520064. PMC 1973944. PMID 17847007.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135925 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026167 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: wingless-type MMTV integration site family".

[pmid11350055-6] Kirikoshi H, Sekihara H, Katoh M (May 2001). "WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells". Biochem. Biophys. Res. Commun. 283 (4): 798–805. doi:10.1006/bbrc.2001.4855. PMID 11350055.

[pmid17847007-7] Adaimy L, Chouery E, Megarbane H, Mroueh S, Delague V, Nicolas E, Belguith H, de Mazancourt P, Megarbane A (October 2007). "Mutation in WNT10A is associated with an autosomal recessive ectodermal dysplasia: the odonto-onycho-dermal dysplasia". Am. J. Hum. Genet. 81 (4): 821–8. doi:10.1086/520064. PMC 1973944. PMID 17847007.

[1]

[2]

[3]

[4]

[5]

[6]

[7]