Whole-cell vaccines are a type of vaccine that has been prepared in the laboratory from entire cells.[1] Such vaccines simultaneously contain multiple antigens to activate the immune system. They induce antigen-specific T-cell responses.[2]
Whole-cell vaccines have been researched in the fields of bacterial infectious disease (as an inactivated vaccine)[3] and cancer (as tumor cells modified to stimulate the immune system by secreting stimulatory molecules).[2] One whole-cell vaccine that sees global use is the whole-cell pertussis vaccine.[3]
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