William Jephson may refer to:
- Sir William Jephson (died 1615), MP for Hampshire
- William Jephson (died 1658), MP for Stockbridge and Cork
- William Jephson (died 1691), MP for East Grinstead and Wycombe
- William Jephson (died 1698), MP for Mallow
- William Jephson (died 1716), MP for Mallow
- William Jephson (died 1779), MP for Mallow
- William Jephson (priest) (died 1720), dean of Lismore
- William Jephson (cricketer) (1873–1956), English cricketer
This disambiguation page lists articles about people with the same name.
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