William Rufus Nicholson (January 8, 1822 - June 7, 1901) was a bishop of the Reformed Episcopal Church and one of the first professors at the Theological Seminary of the Reformed Episcopal Church. Nicholson received an honorary Doctor of Divinity degree from Kenyon College in Ohio. When the Reformed Episcopal Seminary was founded, Nicholson became Dean and one of its first professors. He also wrote a commentary on the book of Colossians titled Oneness with Christ.