William Sampson

William Sampson may refer to:

• William Sampson (author) (1959–2012), a Canadian/British citizen arrested and tortured by the Saudi government between 2000 and 2003
• William Sampson (judge), Chief Justice of the Kentucky Supreme Court during the Civil War
• William Sampson (lawyer) (1764–1836), a United Irishmen lawyer exiled to the United States
• William Sampson (playwright) (1590?–1636?), collaborated with Gervase Markham
• William Harkness Sampson, Methodist minister and educator, founder of Lawrence University
• William T. Sampson (1840–1902), American admiral and commander in the Spanish–American War