William Swain

William Swain may refer to:

• William Moseley Swain (1809–1868), American journalist, publisher and founder
• William Swain (architect) (b.1861), American architect and mayor in Pullman, Washington
• William Swain (diplomat), ambassador from the Marshall Islands to the United Nations
• William Swain (cricketer), English cricketer, businessman and inventor
• Bill Swain, linebacker