Williams Center is an unincorporated community in southeastern Center Township, Williams County, Ohio, United States.[1] It lies at the intersection of State Routes 2 and 576. The headwaters of the Little Lick Creek, a subsidiary of the Maumee River through Lick Creek and the Tiffin River, are located around Williams Center. It is located 4¼ miles (6¾ km) southwest of Bryan, the county seat of Williams County.[2]