Winamac was the name of a number of Potawatomi leaders and warriors beginning in the late 17th century. The name derives from a man named Wilamet, a Native American from an eastern tribe who in 1681 was appointed to serve as a liaison between New France and the natives of the Lake Michigan region. Wilamet was adopted by the Potawatomis, and his name, which meant "Catfish" in his native Eastern Algonquian language, was soon transformed into "Winamac", which means the same thing in the Potawatomi language. The Potawatomi version of the name has been spelled in a variety of ways, including Winnemac, Winamek, and Winnemeg.
The Winamac name became associated with prominent members of the Fish clan of the Potawatomi tribe. In 1701, Winamac or Wilamet was a chief of the Potawatomi villages along the St. Joseph River in what is now the U.S. state of Michigan. This man or another of the same name was an ally of New France who helped negotiate an end to the Fox Wars in the 1730s. Two other Winamacs were prominent during the War of 1812. One was active opponent of the United States, while the other was a U.S. ally. These two Winamacs have often been confused with each other.