YWHAH

YWHAH
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2C63, 2C74
Identifiers
Aliases	YWHAH, YWHA1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
External IDs	OMIM: 113508; MGI: 109194; HomoloGene: 37767; GeneCards: YWHAH; OMA:YWHAH - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	31,957,603 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	33,185,310 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; Brodmann area 10; ; paraflocculus of cerebellum; ; middle frontal gyrus; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; dorsolateral prefrontal cortex; ; orbitofrontal cortex; ; amygdala;
	Top expressed in
	primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; hippocampus proper; ; superior frontal gyrus; ; hypothalamus; ; olfactory bulb; ; neural layer of retina; ; neural tube; ; mesencephalon;
	More reference expression data
	n/a
Gene ontology
Molecular function	sodium channel regulator activity; insulin-like growth factor receptor binding; transmembrane transporter binding; protein domain specific binding; protein binding; glucocorticoid receptor binding; protein heterodimerization activity; enzyme binding; actin binding; identical protein binding;
Cellular component	cytoplasm; cytosol; intercalated disc; plasma membrane; extracellular exosome; cytoplasmic vesicle membrane; mitochondrion; presynapse; glutamatergic synapse;
Biological process	regulation of neuron differentiation; glucocorticoid catabolic process; membrane depolarization during action potential; substantia nigra development; regulation of sodium ion transport; regulation of synaptic plasticity; positive regulation of transcription, DNA-templated; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; negative regulation of dendrite morphogenesis; regulation of sodium ion transmembrane transporter activity; membrane organization; intracellular protein transport; glucocorticoid receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7533
	22629
	ENSG00000128245
	ENSMUSG00000018965
	Q04917
	P68510
	NM_003405
	NM_011738
	NP_003396
	NP_035868
	Wikidata
View/Edit Human	View/Edit Mouse

14-3-3 protein eta also referred to as 14-3-3η is a protein that in humans is encoded by the YWHAH gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000128245 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018965 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000128245 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018965 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[1]

[2]

[3]

[4]