Yasutomi Nishizuka | |
|---|---|
 | |
| Born | July 12, 1932 |
| Died | November 4, 2004 (aged 72) |
| Nationality |  Japan |
| Alma mater | Kyoto University |
| Known for | Protein kinase C |
| Awards | Gairdner Award (1988) Lasker Award (1989) Kyoto Prize (1992) Wolf Prize (1994/95) |
| Scientific career | |
| Fields | Biochemistry |
| Institutions | Kobe University Kyoto University Rockefeller University |
| Doctoral advisor | Osamu Hayaishi |
| Other academic advisors | Fritz Lipmann |
Yasutomi Nishizuka, MJA, ForMemRS (西塚 泰美, Nishizuka Yasutomi, July 12, 1932 – November 4, 2004) [1] was a prominent Japanese biochemist and made important contributions to the understanding of molecular mechanism of signal transduction across the cell membrane. [2] In 1977, he discovered protein kinase C, which plays significant roles in a variety of intracellular signal transduction processes.[3]
He was elected as a foreign member of the Royal Society (ForMemRS) in 1990 and as a member of the Japan Academy (MJA) in 1991.
- ^ Yamamura, H.; Nakamura, S. -I. (2006). "Yasutomi Nishizuka. 12 July 1932 -- 4 November 2004: Elected ForMemRS 1990". Biographical Memoirs of Fellows of the Royal Society. 52: 219–230. doi:10.1098/rsbm.2006.0016. PMID 18543473.
- ^ Nakamura, S. -I.; Yamamura, H. (2010). "Yasutomi Nishizuka: Father of protein kinase C". Journal of Biochemistry. 148 (2): 125–130. doi:10.1093/jb/mvq066. PMID 20668066.
- ^ Takai, Y.; Kishimoto, A.; Inoue, M.; Nishizuka, Y. (1977). "Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum". Journal of Biological Chemistry. 252 (21): 7603–7609. doi:10.1016/S0021-9258(17)41009-X. PMID 199593.