ZBTB20

ZBTB20
Identifiers
Aliases	ZBTB20, DPZF, HOF, ODA-8S, ZNF288, PRIMS, zinc finger and BTB domain containing 20
External IDs	OMIM: 606025; MGI: 1929213; HomoloGene: 9226; GeneCards: ZBTB20; OMA:ZBTB20 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	115,147,288 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	43,642,602 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; caput epididymis; ; tail of epididymis; ; renal medulla; ; corpus callosum; ; Achilles tendon; ; Skeletal muscle tissue of biceps brachii; ; external globus pallidus; ; trigeminal ganglion; ; glutes;
	Top expressed in
	Rostral migratory stream; ; vestibular membrane of cochlear duct; ; utricle; ; median eminence; ; arcuate nucleus; ; ciliary body; ; aortic valve; ; ascending aorta; ; tunica media of zone of aorta; ; retinal pigment epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleic acid binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; metal ion binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; nuclear body; cytoplasm;
Biological process	positive regulation of tumor necrosis factor production; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; negative regulation of gene expression; transcription, DNA-templated; positive regulation of interleukin-6 production; positive regulation of interferon-beta production; positive regulation of glycolytic process; positive regulation of lipid biosynthetic process; lipid homeostasis; cellular response to glucose stimulus;
	Sources:Amigo / QuickGO
Orthologs
	26137
	56490
	ENSG00000181722
	ENSMUSG00000022708
	Q9HC78
	Q8K0L9
NM_001164342; NM_001164343; NM_001164344; NM_001164345; NM_001164346;
	NM_001164347; NM_015642; NM_001348800; NM_001348802; NM_001348803; NM_001348804; NM_001348805; NM_001348801; NM_001393393; NM_001393394; NM_001393395; NM_001393396
	NM_001285805; NM_019778; NM_181058
NP_001157814; NP_001157815; NP_001157816; NP_001157817; NP_001157818;
	NP_001157819; NP_056457; NP_001335729; NP_001335731; NP_001335732; NP_001335733; NP_001335734; NP_001335730
NP_001272734; NP_062752; NP_851401; NP_001380326; NP_001380327;
	NP_001380328
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger and BTB domain-containing protein 20 is a protein that in humans is encoded by the ZBTB20 gene.^[5]^[6]^[7]

There is evidence that ZBTB20 may cause primrose disease.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000181722 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022708 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Harboe TL, Tümer Z, Hansen C, Jensen NA, Tommerup N (Sep 2000). "Assignment of the human zinc finger gene, ZNF288, to chromosome 3 band q13.2 by radiation hybrid mapping and fluorescence in situ hybridisation". Cytogenetics and Cell Genetics. 89 (3–4): 156–157. doi:10.1159/000015600. PMID 10965110. S2CID 36861164.
^ Zhang W, Mi J, Li N, Sui L, Wan T, Zhang J, et al. (April 2001). "Identification and characterization of DPZF, a novel human BTB/POZ zinc finger protein sharing homology to BCL-6". Biochemical and Biophysical Research Communications. 282 (4): 1067–1073. doi:10.1006/bbrc.2001.4689. PMID 11352661.
^ "Entrez Gene: ZBTB20 zinc finger and BTB domain containing 20".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000181722 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022708 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10965110-5] Harboe TL, Tümer Z, Hansen C, Jensen NA, Tommerup N (Sep 2000). "Assignment of the human zinc finger gene, ZNF288, to chromosome 3 band q13.2 by radiation hybrid mapping and fluorescence in situ hybridisation". Cytogenetics and Cell Genetics. 89 (3–4): 156–157. doi:10.1159/000015600. PMID 10965110. S2CID 36861164.

[pmid11352661-6] Zhang W, Mi J, Li N, Sui L, Wan T, Zhang J, et al. (April 2001). "Identification and characterization of DPZF, a novel human BTB/POZ zinc finger protein sharing homology to BCL-6". Biochemical and Biophysical Research Communications. 282 (4): 1067–1073. doi:10.1006/bbrc.2001.4689. PMID 11352661.

[entrez-7] "Entrez Gene: ZBTB20 zinc finger and BTB domain containing 20".

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