ZNF366

ZNF366
Identifiers
Aliases	ZNF366, DCSCRIPT, zinc finger protein 366, DC-SCRIPT
External IDs	OMIM: 610159; MGI: 2178429; HomoloGene: 17637; GeneCards: ZNF366; OMA:ZNF366 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q13.2|5q13.2 Start 72,439,903 bp[1] End 72,507,410 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 D1 Start 99,321,331 bp[2] End 99,387,164 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve testicle epithelium of colon smooth muscle tissue gonad apex of heart appendix left ventricle lymph node subcutaneous adipose tissue Top expressed in lung muscle of thigh quadriceps femoris muscle muscle tissue spleen skeletal muscle tissue white adipose tissue adrenal gland cerebellum human kidney More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding estrogen receptor binding protein binding transcription corepressor activity metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process negative regulation of transcription by RNA polymerase II negative regulation of intracellular estrogen receptor signaling pathway regulation of transcription, DNA-templated transcription, DNA-templated response to estrogen Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 167465 238803 Ensembl ENSG00000178175 ENSMUSG00000050919 UniProt Q8N895 Q6NS86 RefSeq (mRNA) NM_152625 NM_001004149 RefSeq (protein) NP_689838 NP_001004149 Location (UCSC) Chr 5: 72.44 – 72.51 Mb Chr 13: 99.32 – 99.39 Mb PubMed search [3] [4]
Wikidata
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Zinc finger protein 366, also known as DC-SCRIPT (Dendritic cell-specific transcript), is a protein that in humans is encoded by the ZNF366 gene.^[5] The ZNF366 gene was first identified in a DNA comparison study between 85 kb of Fugu rubripes sequence containing 17 genes with its homologous loci in the human draft genome.^[6]