ZNF451

ZNF451
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5D2M
Identifiers
Aliases	ZNF451, COASTER, dJ417I1.1, zinc finger protein 451, ZATT
External IDs	OMIM: 615708; MGI: 2137896; HomoloGene: 9188; GeneCards: ZNF451; OMA:ZNF451 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	57,170,305 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	33,853,676 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; Achilles tendon; ; trabecular bone; ; tibia; ; right testis; ; bone marrow; ; nipple; ; left testis; ; lower lobe of lung; ; sural nerve;
	Top expressed in
	spermatid; ; Rostral migratory stream; ; medial ganglionic eminence; ; zygote; ; secondary oocyte; ; tail of embryo; ; genital tubercle; ; Gonadal ridge; ; primary oocyte; ; trigeminal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SUMO ligase activity; transcription corepressor activity; protein binding; metal ion binding; nucleic acid binding; transferase activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding;
Cellular component	PML body; nucleus; nucleoplasm; histone methyltransferase complex;
Biological process	negative regulation of transcription initiation from RNA polymerase II promoter; negative regulation of histone H3-K9 acetylation; regulation of transcription, DNA-templated; negative regulation of transforming growth factor beta receptor signaling pathway; protein sumoylation; transcription, DNA-templated; regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	26036
	98403
	ENSG00000112200
	ENSMUSG00000042197
	Q9Y4E5
	Q8C0P7
	NM_001031623; NM_001257273; NM_015555
	NM_001290699; NM_001290700; NM_133817; NM_001359274; NM_001359275
	NP_001026794; NP_001244202; NP_056370
	NP_001277628; NP_001277629; NP_598578; NP_001346203; NP_001346204
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 451 is a novel nuclear protein that in humans is encoded by the ZNF451 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112200 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042197 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (February 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
^ "Entrez Gene: ZNF451 zinc finger protein 451".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112200 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042197 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9628581-5] Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (February 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.

[entrez-6] "Entrez Gene: ZNF451 zinc finger protein 451".

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