ZNF638

ZNF638
Identifiers
Aliases	ZNF638, NP220, ZFML, Zfp638, zinc finger protein 638
External IDs	OMIM: 614349; MGI: 1203484; HomoloGene: 7447; GeneCards: ZNF638; OMA:ZNF638 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	71,435,069 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	83,966,532 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; anterior pituitary; ; ventricular zone; ; right uterine tube; ; tibial nerve; ; epithelium of colon; ; sural nerve;
	Top expressed in
	genital tubercle; ; tail of embryo; ; ventricular zone; ; spermatocyte; ; ganglionic eminence; ; zygote; ; granulocyte; ; pineal gland; ; neural layer of retina; ; cerebellar cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; DNA binding; zinc ion binding; double-stranded DNA binding; nucleic acid binding; RNA binding;
Cellular component	cytoplasm; nuclear speck; intracellular membrane-bounded organelle; nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; RNA splicing;
	Sources:Amigo / QuickGO
Orthologs
	27332
	18139
	ENSG00000075292
	ENSMUSG00000030016
	Q14966
	Q61464
	NM_001014972; NM_001252612; NM_001252613; NM_014497
	NM_001166371; NM_008717; NM_001355284; NM_001355285; NM_001355286
	NP_001014972; NP_001239541; NP_001239542; NP_055312
NP_001159843; NP_032743; NP_001342213; NP_001342214; NP_001342215;
	NP_001393000; NP_001393001; NP_001393002; NP_001393003; NP_001393004; NP_001393005; NP_001393006; NP_001393007; NP_001393008; NP_001393009; NP_001393010; NP_001393011; NP_001393012; NP_001393013
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.^[5]^[6]

The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000075292 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030016 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Inagaki H, Matsushima Y, Nakamura K, Ohshima M, Kadowaki T, Kitagawa Y (Jul 1996). "A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain". J Biol Chem. 271 (21): 12525–31. doi:10.1074/jbc.271.21.12525. PMID 8647861.
^ ^a ^b "Entrez Gene: ZNF638 zinc finger protein 638".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000075292 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030016 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8647861-5] Inagaki H, Matsushima Y, Nakamura K, Ohshima M, Kadowaki T, Kitagawa Y (Jul 1996). "A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain". J Biol Chem. 271 (21): 12525–31. doi:10.1074/jbc.271.21.12525. PMID 8647861.

[entrez-6] "Entrez Gene: ZNF638 zinc finger protein 638".

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