ZNF730

ZNF730 or zinc finger protein 730 is a protein which in humans is encoded by the ZNF730 gene. It is located on the short arm of chromosome 19.[1] Zinc finger protein 730 is speculated to play a role in transcriptional regulation in acute myeloid leukemia and endometrial cancer. This is because ZNF730 was found to be expressed in higher levels in endometrial cancerous tumor samples and has been reported as a core binding factor in acute myeloid leukemia.[2] Zinc Finger protein 730 is a C2H2-type zinc finger protein containing a β/β/α structure, held in place by a Zinc ion. The C2H2-type protein motifs can regulate transcription by recognizing and binding to DNA sequences.[3]

  1. ^ "ZNF730 zinc finger protein 730 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2024-07-25.
  2. ^ "GWAS Catalog Gene ZNF730 zinc finger protein 730 [Homo sapiens (human)]". www.ebi.ac.uk/gwas/home. Retrieved 2024-07-25.
  3. ^ "Zinc Finger C2H2 Type". www.ebi.ac.uk/interpro/. Retrieved 2024-07-25.