Zinc transporter ZIP9

SLC39A9
Identifiers
AliasesSLC39A9, ZIP-9, ZIP9, solute carrier family 39 member 9
External IDsMGI: 1914820; HomoloGene: 6935; GeneCards: SLC39A9; OMA:SLC39A9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_026244

RefSeq (protein)

NP_080520

Location (UCSC)Chr 14: 69.4 – 69.46 MbChr 12: 80.69 – 80.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc transporter ZIP9, also known as Zrt- and Irt-like protein 9 (ZIP9) and solute carrier family 39 member 9, is a protein that in humans is encoded by the SLC39A9 gene.[5] This protein is the 9th member out of 14 ZIP family proteins, which is a membrane androgen receptor (mAR) coupled to G proteins, and also classified as a zinc transporter protein.[5][6][7][8] ZIP family proteins transport zinc metal from the extracellular environment into cells through cell membrane.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000029364Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048833Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Thomas P, Converse A, Berg HA (May 2017). "ZIP9, a novel membrane androgen receptor and zinc transporter protein". General and Comparative Endocrinology. 257: 130–136. doi:10.1016/j.ygcen.2017.04.016. PMID 28479083.
  6. ^ a b Eide DJ (February 2004). "The SLC39 family of metal ion transporters". Pflügers Archiv. 447 (5): 796–800. doi:10.1007/s00424-003-1074-3. PMID 12748861. S2CID 11765308.
  7. ^ Berg AH, Rice CD, Rahman MS, Dong J, Thomas P (November 2014). "Identification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: I. Discovery in female atlantic croaker and evidence ZIP9 mediates testosterone-induced apoptosis of ovarian follicle cells". Endocrinology. 155 (11): 4237–49. doi:10.1210/en.2014-1198. PMC 4197986. PMID 25014354.
  8. ^ Thomas P, Pang Y, Dong J, Berg AH (November 2014). "Identification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: II. Role of human ZIP9 in testosterone-induced prostate and breast cancer cell apoptosis". Endocrinology. 155 (11): 4250–65. doi:10.1210/en.2014-1201. PMC 4197988. PMID 25014355.