Protein found in humans
Zinc transporter ZIP9 , also known as Zrt- and Irt-like protein 9 (ZIP9 ) and solute carrier family 39 member 9 , is a protein that in humans is encoded by the SLC39A9 gene .[ 5] This protein is the 9th member out of 14 ZIP family proteins, which is a membrane androgen receptor (mAR) coupled to G proteins , and also classified as a zinc transporter protein .[ 5] [ 6] [ 7] [ 8] ZIP family proteins transport zinc metal from the extracellular environment into cells through cell membrane .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000029364 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048833 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ a b Thomas P, Converse A, Berg HA (May 2017). "ZIP9, a novel membrane androgen receptor and zinc transporter protein". General and Comparative Endocrinology . 257 : 130–136. doi :10.1016/j.ygcen.2017.04.016 . PMID 28479083 .
^ a b Eide DJ (February 2004). "The SLC39 family of metal ion transporters". Pflügers Archiv . 447 (5): 796–800. doi :10.1007/s00424-003-1074-3 . PMID 12748861 . S2CID 11765308 .
^ Berg AH, Rice CD, Rahman MS, Dong J, Thomas P (November 2014). "Identification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: I. Discovery in female atlantic croaker and evidence ZIP9 mediates testosterone-induced apoptosis of ovarian follicle cells" . Endocrinology . 155 (11): 4237–49. doi :10.1210/en.2014-1198 . PMC 4197986 . PMID 25014354 .
^ Thomas P, Pang Y, Dong J, Berg AH (November 2014). "Identification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: II. Role of human ZIP9 in testosterone-induced prostate and breast cancer cell apoptosis" . Endocrinology . 155 (11): 4250–65. doi :10.1210/en.2014-1201 . PMC 4197988 . PMID 25014355 .