"Tropheryma"

"Tropheryma"
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Micrococcales
Family: "Tropherymataceae"
Nouioui et al. 2018[2]
Genus:
"Tropheryma"

La Scola et al. 2001[1]
Species:
"T. whipplei"
Binomial name
"Tropheryma whipplei"
La Scola et al. 2001[1]
Synonyms[3]
  • Tropheryma whippelii Relman et al. 1992

"Tropheryma whipplei" is a bacterium that is the causative organism of Whipple's disease,[1] and rarely, endocarditis.

While "T. whipplei" is categorized with the Gram-positive Actinomycetota, the organism is commonly found to be Gram-positive or Gram-indeterminate when stained in the laboratory.[1] Whipple himself probably observed the organisms as rod-shaped structures with silver stain in his original case.[4]

  1. ^ a b c d La Scola B, Fenollar F, Fournier PE, Altwegg M, Mallet MN, Raoult D (July 2001). "Description of Tropheryma whipplei gen. nov., sp. nov., the Whipple's disease bacillus". International Journal of Systematic and Evolutionary Microbiology. 51 (Pt 4): 1471–9. doi:10.1099/00207713-51-4-1471. PMID 11491348.
  2. ^ Nouioui, Imen; Carro, Lorena; García-López, Marina; Meier-Kolthoff, Jan P.; Woyke, Tanja; Kyrpides, Nikos C.; Pukall, Rüdiger; Klenk, Hans-Peter; Goodfellow, Michael; Göker, Markus (2018). "Genome-based taxonomic classification of the phylum Actinobacteria". Frontiers in Microbiology. 9 (2007): 1–119. doi:10.3389/fmicb.2018.02007. PMC 6113628. PMID 30186281.
  3. ^ Liang Z, La Scola B, Raoult D (January 2002). "Monoclonal antibodies to immunodominant epitope of Tropheryma whipplei". Clinical and Diagnostic Laboratory Immunology. 9 (1): 156–9. doi:10.1128/CDLI.9.1.156-159.2002. PMC 119894. PMID 11777846.
  4. ^ Whipple GH. (1907). "A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues". Johns Hopkins Hospital Bulletin. 18: 382–91.