1-Tetralone

1-Tetralone
Structural formula of 1-tetralone
Ball-and-stick model of the 1-tetralone molecule
Names
Preferred IUPAC name
3,4-Dihydro-2H-naphthalen-1-one
Other names
α-Tetralone; 1-Tetralone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.007.692 Edit this at Wikidata
EC Number
  • 208-460-6
UNII
  • InChI=1S/C10H10O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6H,3,5,7H2 ☒N
    Key: XHLHPRDBBAGVEG-UHFFFAOYSA-N ☒N
  • InChI=1/C10H10O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6H,3,5,7H2
    Key: XHLHPRDBBAGVEG-UHFFFAOYAD
  • C1CC2=CC=CC=C2C(=O)C1
Properties
C10H10O
Molar mass 146.189 g·mol−1
Appearance colorless liquid
Density 1.099 g·cm−3 (25 °C)[1]
Melting point 2–7 °C[1]
Boiling point 255–257 °C[2]
113–116 °C (8 hPa)[1]
insoluble[3]
Solubility soluble in organic solvents
Vapor pressure 2.7 Pa (20 °C)[3]
1.5672
Hazards
GHS labelling:[4]
GHS07: Exclamation mark
Warning
H302
P264, P270, P301+P317, P330, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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1-Tetralone is a bicyclic aromatic hydrocarbon and a ketone. In terms of its structure, it can also be regarded as benzo-fused cyclohexanone. It is a colorless oil with a faint odor.[5] It is used as starting material for agricultural and pharmaceutical agents. The carbon skeleton of 1-tetralone is found in natural products such as Aristelegone A (4,7-dimethyl-6-methoxy-1-tetralone) from the family of Aristolochiaceae used in traditional Chinese medicine.[6]

  1. ^ a b c Sigma-Aldrich Co., α-Tetralon. Retrieved on 25. November 2017.
  2. ^ William M. Haynes (2016), CRC Handbook of Chemistry and Physics, 97th Edition, Boca Raton, FL, U.S.A.: CRC Press, pp. 3–504, ISBN 978-1-4987-5429-3
  3. ^ a b "alpha-Tetralone 529-34-0 | TCI Deutschland GmbH". www.tcichemicals.com (in German). Retrieved 2017-12-17.
  4. ^ "1-Tetralone". pubchem.ncbi.nlm.nih.gov.
  5. ^ Cite error: The named reference Snyder was invoked but never defined (see the help page).
  6. ^ P.-C. Kuo; Y.-C. Li; T.-S. Wu (2012), "Chemical constituents and pharmacology of the Aristolochia species", EJTCM, vol. 2, no. 4, pp. 249–266, doi:10.1016/S2225-4110(16)30111-0, PMC 3942903, PMID 24716140