| 101st Intelligence Squadron | |
|---|---|
 101st Observation Squadron, Massachusetts NG (divisional aviation, 26th Division) Curtis O-11,about 1925 | |
| Active | 18 November 1921–Present |
| Country |  United States |
| Allegiance |  Massachusetts |
| Branch |  Air National Guard |
| Type | Squadron |
| Role | Intelligence, Surveillance and Reconnaissance (ISR) |
| Part of | Massachusetts Air National Guard |
| Garrison/HQ | Otis Air National Guard Base, Mashpee, Massachusetts |
| Motto(s) | "Omnis Vir Tigris "Everyone A Tiger"" |
| Engagements | World War I World War II |
| Insignia | |
| 101st Intelligence Squadron emblem |  |
The United States Air Force's 101st Intelligence Squadron (101 IS), Massachusetts Air National Guard, is an intelligence unit assigned to the 102nd Intelligence Wing and located at Otis Air National Guard Base, Massachusetts. From its creation in 1921 to its mission change in 2008, the 101st was the mainstay of aerospace defence for the Northeastern United States. The 101st was deployed during the Berlin Crisis to France and was also deployed to Panama during Operation Coronet Nighthawk. It also participated in Operation Northern Watch. During the September 11 attacks, the 101st was the first Air Force unit to send aircraft toward New York City, but they arrived too late to help stop the attacks.
Base downsizing through the Base Realignment and Closure (BRAC) process removed the wing's F-15C Eagles beginning in 2007, leaving the 101st with an intelligence gathering mission that will be fully active starting in 2010. It is one of three Air National Guard wings that works with the Air Force Intelligence, Surveillance and Reconnaissance Agency.