11-Nor-9-carboxy-THC

Not to be confused with Tetrahydrocannabinolic acid.
11-Nor-9-carboxy-THC
THC-11-oic acid molecule
Clinical data
Pregnancy
category
  • Inconclusive
Routes of
administration		Variable
Pharmacokinetic data
BioavailabilityVariable
MetabolismVariable
Elimination half-life5.2 to 6.2 days [1]
ExcretionVariable
Identifiers
  • 1-Hydroxy-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-9-carboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H28O4
Molar mass344.451 g·mol−1
3D model (JSmol)
  • CCCCCc1cc(c2c(c1)OC(C3C2C=C(CC3)C(=O)O)(C)C)O
  • InChI=1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24) checkY
  • Key:YOVRGSHRZRJTLZ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

11-Nor-9-carboxy-Δ9-tetrahydrocannabinol (11-COOH-THC or THC-COOH), often referred to as 11-nor-9-carboxy-THC or THC-11-oic acid, is the main secondary metabolite of tetrahydrocannabinol (THC) which is formed in the body after cannabis is consumed.

  1. ^ Schwilke EW, Schwope DM, Karschner EL, Lowe RH, Darwin WD, Kelly DL, et al. (December 2009). "Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC". Clinical Chemistry. 55 (12): 2180–2189. doi:10.1373/clinchem.2008.122119. PMC 3196989. PMID 19833841.