Indiana re-elected its member August 3, 1818.
| District | Incumbent | This race | |||
|---|---|---|---|---|---|
| Member | Party | First elected | Results | Candidates | |
| Indiana at-large | William Hendricks | Democratic-Republican | 1816 | Incumbent re-elected. | √ William Hendricks (Democratic-Republican) 90.5% Reuben W. Nelson 9.5% |