The 1900 United States presidential election in Missouri took place on November 6, 1900. Voters chose 17 electors to represent them in the Electoral College via a popular vote, pitting incumbentRepublicanPresidentWilliam McKinley and his running mate Theodore Roosevelt against the Democratic ticket of challenger William Jennings Bryan and Adlai Stevenson. Missouri gave Bryan 51.48 percent of the vote versus McKinley's 45.94 percent, a margin of 5.53%. While losing Missouri, McKinley nevertheless won the national election by a 6.13-point margin.
After 1900 and before 2008, the state voted for the national winner in every election except for 1956 (coincidentally, Missouri voted for Stevenson's grandson in that election). However, that reputation began to fade after voting for losing Republican candidates for two elections in a row in 2008 and 2012. McKinley was the only president in American history to win two terms in office and lose Missouri twice until 2012 and is the only Republican president to ever do so.