| 1946 Jacksonville State Eagle Owls football | |
|---|---|
| Conference | Alabama Intercollegiate Conference |
| Record | 3–5–1 (1–1–1 AIC) |
| Head coach |
|
| Home stadium | College Field |
The 1946 Jacksonville State Eagle Owls football team represented Jacksonville State Teachers College (now known as Jacksonville State University) as a member of the Alabama Intercollegiate Conference (AIC) during the 1946 college football season. Led by first-year head coach Don Salls, the Gamecocks compiled an overall record of 3–5–1 with a mark of 1–1–1 in conference play.