| 1960 Cal Poly Mustangs football | |
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| Conference | California Collegiate Athletic Association |
| Record | 1–5 (1–2 CCAA) |
| Head coach |
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| Home stadium | Mustang Stadium |
| Conf | Overall | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Team | W | L | T | W | L | T | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| No. 9 Fresno State $ | 5 | – | 0 | – | 0 | 9 | – | 1 | – | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Long Beach State | 3 | – | 1 | – | 1 | 5 | – | 3 | – | 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Los Angeles State | 2 | – | 1 | – | 1 | 4 | – | 3 | – | 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cal Poly | 1 | – | 2 | – | 0 | 1 | – | 5 | – | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| UC Santa Barbara | 1 | – | 3 | – | 0 | 2 | – | 5 | – | 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| San Diego State | 0 | – | 5 | – | 0 | 1 | – | 6 | – | 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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The 1960 Cal Poly Mustangs football team represented California Polytechnic State College as a member of the California Collegiate Athletic Association (CCAA) during the 1960 college football season.
Led by 11th-year head coach LeRoy Hughes, Cal Poly compiled an overall record of 1–5 with a mark of 1–2 in conference play, placing fourth in the CCAA. The Mustangs played home games at Mustang Stadium in San Luis Obispo, California.
Tragedy struck following the game at Bowling Green State University on October 29, when the aircraft transporting the team crashed, killing 22 people, including 16 Cal Poly Mustang football players and the team manager. Cal Poly cancelled the rest of their scheduled games, against Los Angeles State, UC Santa Barbara, and Adams State.
The following year, a benefit game was held to raise a memorial fund for the survivors and bereaved families. It was called the Mercy Bowl and was held at the Los Angeles Memorial Coliseum in Los Angeles.
The game between Fresno State and Bowling Green on November 23, 1961, raised more than $200,000.