| Tournament details | |
|---|---|
| Country | Panama |
| City | Panama City |
| Venue(s) | 1 (in 1 host city) |
| Dates | 10–15 February |
| Teams | 4 |
| Final positions | |
| Champions |  Elefantes de Cienfuegos (2nd title) |
| Runner-up |  Marlboro Smokers |
| Tournament statistics | |
| MVP | Camilo Pascual |
The twelfth edition of the Caribbean Series (Serie del Caribe) was a baseball tournament held from February 10 through February 15, 1960 featuring the champion teams from Cuba (Cienfuegos), Panama (Marlboro), Puerto Rico (Caguas) and Venezuela (Rapiños). The format consisted of 12 games, each team facing the other teams twice, and the games were played at Estadio Nacional of Panama City.