The 1960 South Carolina United States Senate election was held on November 8, 1960, to select the U.S. Senator from the state of South Carolina. Popular incumbent Senator Strom Thurmond easily won the Democratic primary and was unopposed in the general election.
This was Thurmond's last Senate race in which he ran as a Democrat; in 1964 he switched parties in opposition to the Democrats' support for the Civil Rights Act of 1964 and continued to serve until he left office in 2003 and was succeeded by Lindsey Graham (R). As of 2023[update], this is the last time that Democrats won South Carolina's Class 2 Senate seat.