The 1972 United States House of Representatives elections in South Carolina were held on November 7, 1972, to select six Representatives for two-year terms from the state of South Carolina. The primary elections were held on August 29 and the runoff elections were held two weeks later on September 12. Five incumbents were re-elected and the only change was in the 6th district where Republican Edward Lunn Young succeeded Democrat John L. McMillan, who was defeated in the Democratic primary. The composition of the state delegation after the elections was four Democrats and two Republicans.