| Tournament details | |
|---|---|
| Dates | February 16 – August 6 |
| Teams | 21 (from 10 associations) |
| Final positions | |
| Champions |  Nacional (2nd title) |
| Runners-up |  Internacional |
| Tournament statistics | |
| Matches played | 75 |
| Goals scored | 160 (2.13 per match) |
The Copa Libertadores 1980 was the 21st edition of the Copa Libertadores, CONMEBOL's annual international club tournament. Nacional of Uruguay won the competition defeating Brazilian club Internacional. Defending champion Olimpia were eliminated in the semifinals.