The 1981 James Hardie 1000 was the 22nd running of the Bathurst 1000 touring car race. It was held on 4 October 1981 at the Mount Panorama Circuit just outside Bathurst. The race was open to cars eligible to the locally developed CAMS Group C touring car regulations with three engine configuration based classes, a system used uniquely for this race.
For the first time the race did not go the full race distance as on lap 121, a six car accident blocked the track at McPhillamy Park Corner. The Ford Falcon of Dick Johnson and John French were leading the race at the time of the accident and were declared the winners, becoming the first Queenslanders to win the race. Bob Morris and British endurance racer John Fitzpatrick, also driving a Falcon finished second. A lap down in third was Allan Moffat and British endurance racing great Derek Bell driving a Mazda RX-7, the best ever result to that point for a Japanese built car.
History was made at Bathurst in 1981. For the first (and as of 2020, the only) time in the races history, a reigning Formula One World Drivers' Champion drove in the Bathurst 1000. This honour fell to Australia's own 1980 World Champion Alan Jones who co-drove with Warren Cullen in Cullen's V8 Holden Commodore.
After 8 wins in the race dating back to Bob Jane and Harry Firth's win in a Ford Falcon XL at Phillip Island in 1962, this would prove to be the last Bathurst 1000 win for the Ford Falcon until 1994. It would also be the 5th and last Bathurst win for the 5.8 L 351 Cleveland V8 engine.