| Tournament details | |
|---|---|
| Host country |  Argentina |
| Venue(s) | 1 (in 1 host city) |
| Dates | 9–14 November |
| Teams | 7 (from 1 confederation) |
| Final positions | |
| Champions |  Cuba (2nd title) |
| Runner-up |  Brazil |
| Third place |  United States |
| Fourth place | Argentina |
| Tournament statistics | |
| Matches played | 15 |
| Goals scored | 793 (52.87 per match) |
The 1981 Pan American Men's Handball Championship was the second edition of the tournament, held in Buenos Aires, Argentina from 9 to 14 November 1981. It acted as the American qualifying tournament for the 1982 World Championship.