| 1981 US Open | |
|---|---|
| Date | September 1–13 |
| Edition | 101st |
| Category | Grand Slam (ITF) |
| Surface | Hardcourt |
| Location | New York City, United States |
| Champions | |
| Men's singles | |
 John McEnroe | |
| Women's singles | |
| Tracy Austin | |
| Men's doubles | |
| Peter Fleming / John McEnroe | |
| Women's doubles | |
| Kathy Jordan / Anne Smith | |
| Mixed doubles | |
Anne Smith /  Kevin Curren | |
| Boys' singles | |
 Thomas Högstedt | |
| Girls' singles | |
| Zina Garrison | |
The 1981 US Open was a tennis tournament played on outdoor hard courts at the USTA National Tennis Center in New York City, United States. It was the 101st edition of the US Open and was held from September 1 to September 13, 1981.