The thirty-third edition of the Caribbean Series (Serie del Caribe) was a baseball competition played in 1991. It was held from February 2 through February 9 with the champion teams from the Dominican Republic, Tigres del Licey; Mexico, Potros de Tijuana; Puerto Rico, Cangrejeros de Santurce, and Venezuela, Cardenales de Lara. All games were held at Bobby Maduro Stadium in Miami, Florida.