| Tournament details | |
|---|---|
| Dates | 28 July – 22 December 1999 |
| Teams | 12 (from 5 associations) |
| Final positions | |
| Champions |  América de Cali (1st title) |
| Runners-up | Santa Fe |
| Tournament statistics | |
| Matches played | 42 |
| Goals scored | 122 (2.9 per match) |
| Top scorer(s) |  Juan Enrique García (6) |
← 1998 2000 → | |
The 1999 Copa Merconorte was the 2nd edition of association football tournament Copa Merconorte held in 1999. América de Cali of Colombia beat Santa Fe also of Colombia in the final.