| 2000 Indianapolis Colts season | |
|---|---|
| Owner | Jim Irsay |
| General manager | Bill Polian |
| Head coach | Jim Mora |
| Home field | RCA Dome |
| Results | |
| Record | 10–6 |
| Division place | 2nd AFC East |
| Playoff finish | Lost Wild Card Playoffs (at Dolphins) 17–23 (OT) |
| Pro Bowlers | QB Peyton Manning RB Edgerrin James WR Marvin Harrison |
The 2000 season was the Indianapolis Colts' 48th in the National Football League (NFL) and their 17th in Indianapolis. They finished second in the AFC East with a 10–6 record, but lost in overtime to their division rival Miami Dolphins in the wildcard round of the playoffs.
As in the previous season, the Colts once again sent Peyton Manning, Edgerrin James and Marvin Harrison to the Pro Bowl at the end of the season.