The 2000 NASCAR Craftsman Truck Series was the sixth season of the Craftsman Truck Series, the third highest stock car racing series sanctioned by NASCAR in the United States. Greg Biffle of Roush Racing was crowned the series champion, giving Ford its first Truck Series championship and ending Chevrolet's five-year streak.
The season was marred by the death of Tony Roper in the penultimate race of the season at Texas Motor Speedway. His death was the third of three driver fatalities across the nationwide NASCAR circuits in 2000 that included Kenny Irwin Jr. and Adam Petty.