2001 Major League Lacrosse season

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The 2001 Major League Lacrosse season was the inaugural season of the new semi-professional men's field lacrosse league. The league began play with six founding teams: Baltimore Bayhawks, Boston Cannons, Bridgeport Barrage, Long Island Lizards, New Jersey Pride and Rochester Rattlers. Each team played a 14-game regular season schedule that ended with a championship game on September 3, 2001.

Major League Lacrosse (MLL) played its first game on June 7 when Baltimore defeated Long Island 16–13 score at Homewood Field in Baltimore. Baltimore's Chris Turner scored the first goal in MLL regular season history. Those same two teams met in the Steinfeld Cup, the championship trophy named for co-founder Jake Steinfeld, with the Lizards turning the tables and beating the Bayhawks 15–11.