| 2001 US Open | |
|---|---|
| Date | August 27 – September 9 |
| Edition | 121st |
| Category | Grand Slam (ITF) |
| Surface | Hardcourt |
| Location | New York City, U.S. |
| Champions | |
| Men's singles | |
 Lleyton Hewitt | |
| Women's singles | |
 Venus Williams | |
| Men's doubles | |
 Wayne Black / Kevin Ullyett | |
| Women's doubles | |
| Lisa Raymond / Rennae Stubbs | |
| Mixed doubles | |
| Todd Woodbridge / Rennae Stubbs | |
| Boys' singles | |
 Gilles Müller | |
| Girls' singles | |
 Marion Bartoli | |
| Boys' doubles | |
 Tomáš Berdych /  Stéphane Bohli | |
| Girls' doubles | |
 Galina Fokina / Svetlana Kuznetsova | |
The 2001 US Open was held between August 27 – September 9, 2001. It was the final Grand Slam event of 2001.
Marat Safin was unsuccessful in his title defence, being defeated in the semifinals by Pete Sampras in a rematch of the 2000 final, while Venus Williams was successful in her title defense, beating her sister Serena in the women's final. 20-year-old Australian Lleyton Hewitt won the men's title, defeating Sampras in the final. It was the second consecutive US Open final defeat for Sampras.